NASHRES

First scoring system to predict NASH resolution after lifestyle intervention.

Nonalcoholic steatohepatitis (NASH) may progress to cirrhosis and its associated complications.

Lifestyle modification is the mainstay to induce weight loss in overweight/obese nonalcoholic fatty liver disease (NAFLD).

Resolution of steatohepatitis without fibrosis impairment is a reliable method to measure histologic changes on paired liver biopsies of NAFLD patients.

Liver biopsy is invasive, expensive, and may result in complications and thus establishing non-invasive alternatives are an important priority.

The introduction of this scoring system as a predictor of steatohepatitis resolution into daily practice should be relatively simple and will not result in extra cost.